ErbB Receptor Signaling: Methods and Protocols by Zhixiang Wang (English) Hardco

Description: ErbB Receptor Signaling by Zhixiang Wang This volume contains protocols specifically designed for studying cell signaling mediated by ErbB receptors, all applicable to the study of a broad range of ErbB receptor-mediated signaling from basic research to clinic applications, from cultured cells to various animal models and primary cancer cells from patients. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description This volume contains protocols specifically designed for studying cell signaling mediated by ErbB receptors, all applicable to the study of a broad range of ErbB receptor-mediated signaling from basic research to clinic applications, from cultured cells to various animal models and primary cancer cells from patients. After some overviews, the book continues by covering common protocols for studying various aspects of ErbB receptor-mediated cell signaling, newly-developed methods in biomedical research that are also widely-used in the study of ErbB receptor signaling, epidermal growth factor receptor (EGFR) signaling in Drosophila, as well as protocols for studying ErbB receptor signaling in various animal model systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Detailed and easy-to-follow, ErbB Receptor Signaling: Methods and Protocols serves as an ideal guide for researchers who are studying the cell signaling mediated by ErbB receptors and other receptor tyrosine kinases. Back Cover This volume contains protocols specifically designed for studying cell signaling mediated by ErbB receptors, all applicable to the study of a broad range of ErbB receptor-mediated signaling from basic research to clinic applications, from cultured cells to various animal models and primary cancer cells from patients. After some overviews, the book continues by covering common protocols for studying various aspects of ErbB receptor-mediated cell signaling, newly-developed methods in biomedical research that are also widely-used in the study of ErbB receptor signaling, epidermal growth factor receptor (EGFR) signaling in Drosophila, as well as protocols for studying ErbB receptor signaling in various animal model systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Detailed and easy-to-follow, ErbB Receptor Signaling: Methods and Protocols serves as an ideal guide for researchers who are studying the cell signaling mediated by ErbB receptors and other receptor tyrosine kinases. Table of Contents ErbB Receptors and Cancer.- New Insights from Drosophila into the Regulation of EGFR Signaling.- C. elegans Vulva Induction: An In Vivo Model to Study Epidermal Growth Factor Receptor Signaling and Trafficking.- Targeting HER2 in Advanced Breast Cancer.- Methods to Investigate EGFR Ubiquitination.- Dimerization Assessment of Epithelial Growth Factor Family of Receptor Tyrosine Kinases by Using Cross-Linking Reagent.- Application of Immunofluorescence Staining to Study ErbB Family of Receptor Tyrosine Kinases.- Activation of Endosome-Associated Inert EGF Receptor Following Internalization.- Two-Pulse Endosomal Stimulation of Receptor Tyrosine Kinases Induces Cell Proliferation.- Study of EGFR Signalling/Endocytosis by Site-Directed Mutagenesis.- Using Percoll Gradient Fractionation to Study the Endocytic Trafficking of the EGFR.- Analysis of Epidermal Growth Factor Receptor-Induced Cell Motility by Wound Healing Assay.- Cell Cycle Synchronization of HeLa Cells to Assay EGFR Pathway Activation.- Analysis of Constitutive EGFR Signaling Regulating IRF3 Transcriptional Activity in Cancer Cells.- Measurement of Epidermal Growth Factor Receptor-Derived Signals Within Plasma Membrane Clathrin Structures.- Studying Non-Proliferative Roles for Egfr Signaling in Tissue Morphogenesis Using Dorsal Closure of the Drosophila Embryo.- Analysis of Epithelial-Mesenchymal Transition Induced by Overexpression of Twist.- Assessment of Specificity of an Adenovirus Targeted to HER3/4.- Isolation of Human Mesenchymal Stem Cells for Studying ErbB Receptor Signaling. Feature Includes cutting-edge methods and protocols for the study of ErbB receptor signaling Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts Details ISBN1493972189 Publisher Humana Press Inc. Year 2017 ISBN-10 1493972189 ISBN-13 9781493972180 Format Hardcover Edition 1st Imprint Humana Press Inc. Subtitle Methods and Protocols Place of Publication Totowa, NJ Country of Publication United States Edited by Zhixiang Wang DEWEY 571.6 Pages 303 Language English Media Book Publication Date 2017-08-09 Short Title ErbB Receptor Signaling DOI 10.1007/978-1-4939-7219-7 Series Number 1652 AU Release Date 2017-08-09 NZ Release Date 2017-08-09 US Release Date 2017-08-09 UK Release Date 2017-08-09 Author Zhixiang Wang Birth 1826 Death 1890 Affiliation Temple University, Philadelphia Position EDITOR Qualifications MD Edition Description 1st ed. 2017 Series Methods in Molecular Biology Alternative 9781493984206 Audience Professional & Vocational Illustrations 41 Illustrations, color; 13 Illustrations, black and white; X, 303 p. 54 illus., 41 illus. in color. We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:130978420;

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